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Effect of danaparoid sodium (DA) on high mobility group box 1 (HMGB1) production by lipopolysaccharide (LPS)-stimulated murine macrophages. Murine macrophages treated without or with DA (1, 15, 50 U/ml) were stimulated with LPS (100 ng/ml) for 20 h. Supernatants and cell protein were prepared and examined by enzyme linked immunosorbent assay (ELISA). All data are expressed as means ± SD. *Denotes a significant difference compared with the LPS group (p < 0.05).
