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. 2008 Apr 2;12(2):R43. doi: 10.1186/cc6851

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Copyright © 2008 Hagiwara et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of danaparoid sodium (DA) on interleukin (IL)-6 and tumour necrosis factor (TNF)α production by lipopolysaccharide (LPS)-stimulated murine macrophages. Murine macrophages treated with or without DA (50 U/ml) were stimulated with LPS (100 ng/ml) for the indicated time. Supernatants were collected and IL-6 and TNFα levels were determined by enzyme linked immunosorbent assay (ELISA). All data are expressed as mean ± SD. *Denotes a significant difference compared with the LPS-treated cells (p < 0.05).