Table 2.
Data relating to infusions of DrotAA
| Infusion-related data | All admissions receiving DrotAA (n = 1,292) |
| Time from unit admission to start of infusion (hours; median [IQR]) | 19.5 (9.3–35.3) |
| Received complete 96-hour infusion (n [%]) | 896 (69.9) |
| Reason for not receiving complete infusion (n [%]) | |
| Deterioration/treatment withdrawn/died | 195 (50.8) |
| Actual/possible bleeding | 91 (23.7) |
| Patient improved/left ward | 34 (8.9) |
| Other intervention/treatment outside unit | 16 (4.2) |
| Criteria reassessed/incorrect | 9 (2.3) |
| Timing error | 8 (2.1) |
| Other intervention/treatment in unit | 5 (1.3) |
| Macro/micro drug supply issues | 4 (1.0) |
| Infused over shorter time period | 1 (0.3) |
| No reason given/not known | 21 (5.5) |
| Interruption in the infusion (n [%]) | 304 (24.0) |
| Time from start of infusion to interruption (hours; median [IQR]) | 24.0 (13.2–49.0) |
| Duration of interruption (hours; median [IQR]) | 5 (3–10) |
| Reason for interruption (n [%]) | |
| Lines/catheters/cannula/drain/dressing-inserted/changed/removed/re-sited/fell out | 144 (48.0) |
| To theatre | 48 (16.0) |
| Bleeding related (actual/suspected) | 35 (11.7) |
| Intervention off unit | 15 (5.0) |
| Tracheostomy | 15 (5.0) |
| Intervention on unit | 11 (3.7) |
| In error | 10 (3.3) |
| Macro/micro drug supply issues | 10 (3.3) |
| Patients condition improved/left unit | 1 (0.3) |
| No reason given/not known | 11 (3.7) |
IQR, interquartile range.