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. 2008 Apr 24;12(2):R59. doi: 10.1186/cc6883

Table 2.

Diagnostic performance of the eosinophil count and the C-reactive protein level in the prediction of sepsis on intensive care unit admission

Variable Noninfection versus infection SIRS versus infection
C-reactive protein level Eosinophil cell count C-reactive protein level Eosinophil cell count

Cutoff value >70 mg/l <50 cells/mm3 >80 mg/l <40 cells/mm3
Sensitivity (%) 68 (59 to 76) 80 (71 to 86) 68 (59 to 79) 80 (71 to 86)
Specificity (%) 61 (47 to 74) 91 (79 to 96) 55 (32 to 76) 80 (55 to 93)
Positive likelihood ratio 1.77 (1.25 to 2.51) 9.12 (3.9 to 21) 1.52 (0.92 to 2.50) 4.00 (1.65 to 9.65)
Negative likelihood ratio 0.52 (0.39 to 0.69) 0.21 (0.15 to 0.31) 0.57 (0.41 to 0.81) 0.25 (0.17 to 0.36)
Area under the receiver operating characteristic curve 0.77 (0.70 to 0.84) 0.89 (0.83 to 0.94) 0.77 (0.67 to 0.87) 0.84 (0.74 to 0.94)

Data in parentheses are 95% confidence intervals. Noninfection, negative + systemic inflammatory response syndrome (SIRS); infection, sepsis + severe sepsis + septic shock.