Figure 3.

Web interface and output of MAPPIS. (A) Entrance webserver page. (B) An option for the automatic selection of the interacting protein chains (if not specified manually). Two protein chains are considered as interacting if there are at least five atoms of one chain that are within the distance of 6.0 Å from the other. (C) Example of an output page, which details the common pattern of matched interactions. Each pair of rows details a shared interaction, which is defined by the interacting pseudocenters from two different chains of a PPI. As in MultiBind each three columns present the details of a specific pseudocenter of a PPI. (D) A default Jmol visualization of the aligned complexes. The shared physico-chemical properties are represented as in Figure 1. The corresponding common interactions are represented as yellow sticks.