Figure 2.
Secretory vesicle trajectories within growth cones. (A) Examples from vesicles labeled with the inducible construct. (B) Examples detected by TIRFM. The xy trajectory and the simultaneous movement over time perpendicular to the substrate are shown for two vesicles. Images were acquired at 1 Hz. Note that motion in all dimensions appears to be random. Furthermore, a great range of vesicle speeds is evident.