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. 2008 Jul 23;3(7):e2766. doi: 10.1371/journal.pone.0002766

Figure 2. Serum concentrations of angiogenic factors in normotensive women, women with pre-eclampsia and women with gestational hypertension who received methyldopa.

Figure 2

Mean serum sFlt-1 (a), PlGF (b) and sEng (c) concentrations in normotensives (controls), women with pre-eclampsia and women with gestational hypertension according to gestational age (GA) interval [early onset <34 weeks (41 controls, 28 PE, 13 GH) and late onset ≥34 weeks (39 controls, 23 PE, 16 GH)]. Error bars represent standard errors. Comparison of controls and cases (with PE or GH) was performed after logarithmic transformation. Levels before and after alpha methyldopa therapy are shown for women with pre-eclampsia and women with gestational hypertension. The levels in the three groups were compared using ANOVA with Bonferroni Dunn's posthoc tests. The levels before and after antihypertensive therapy are compared using the paired t test. ****P<0.0001, ***P<0.001, **P<0.01, *P<0.05. P values are shown only for differences which are statistically significant.