Table 1. Baseline characteristics of the study groups in whom serum levels of angiogenic factors were measured, according to gestational age at recruitment.
| <34+0 weeks | ≥34+0 weeks | |||||||
| Controls | PE | GH | P value | Controls | PE | GH | P value | |
| n | 41 | 28 | 13 | 39 | 23 | 16 | ||
| Age (years) † | 31±4 | 30±5 | 32±4 | 0.6 | 31±4 | 30±4 | 32±5 | 0.2 |
| BMI (kg/m2) † | 27±4 | 30±4 | 27±4 | 0.07 | 28±3 | 27±5 | 29±5 | 0.2 |
| Nulliparity [n (%)] | 25 (61) | 20 (71) | 7 (54) | 0.6 | 21 (53) | 16 (70) | 9 (56) | 0.3 |
| Current smoker [n (%)] | 1 (2) | 0 (0) | 0 (0) | 1 | 2 (5) | 1 (4) | 0 (0) | 1 |
| Caucasian [n (%)] | 20 (48) | 13 (46) | 7 (54) | 0.7 | 23 (59) | 13 (57) | 9 (56) | 0.4 |
| GA at recruitment (days) † | 30±1.3 | 30±0.4 | 30.4±0.8 | 0.5 | 36.6±2.4 | 36±2.3 | 36.4±2 | 0.4 |
| GA at delivery (days) † | 39.7±2.3 | 33±1.7 | 36.7±2.9 | <0.001 | 39.8±1.6 | 37.3±2 | 38.6±2.3 | <0.001 |
| Birth weight (grammes) † | 3398±529 | 1685±204 | 2725±198 | <0.001 | 3405±526 | 2896±689 | 3174±591 | <0.001 |
| Mean BP (mmHg) | 85±12 | 126.6±12 | 125.1±12 | <0.0001 | 85±11 | 121.1±11.1 | 114.5±6.1 | <0.0001 |
| Mean Pulsatility Index (PI) | 0.76±0.1 | 1.51±0.5 | 0.84±0.1 | <0.0001 | 0.59±0.1 | 0.85±0.2 | 0.61±0.1 | <0.0001 |
| Interval between samples (hours) | 32±4 | 34±3 | 38±6 | 39±7 | ||||
BMI = body mass index.
GA = gestational age.
Mean BP = mean blood pressure.
PE = pre-eclampsia.
GH = gestational hypertension.
†
Data presented as mean±SD and analyzed by one-way ANOVA with Bonferroni post hoc analysis.