Skip to main content
NCBI home page
The Ulster Medical Journal logoLink to The Ulster Medical Journal
. 1986 Oct;55(2):165–171.

Posterior fossa haemangioblastomas in Northern Ireland: a clinico-epidemiological study

C P Chee, I C Bailey
PMCID: PMC2448363  PMID: 3811016

Abstract

A retrospective study of 25 patients who presented with posterior fossa haemangioblastomas to the Northern Ireland Regional Neurosurgical Centre over the past 25 years has been carried out. The epidemiological and clinical features and the results after operative treatment are presented and compared with other series. Posterior fossa haemangioblastomas were more common in female than in male patients and solid tumours accounted for 40% of all cases. While only two patients had associated polycythaemia, five patients (20%) were found to have persistent leucocytosis pre-operatively, while 24% had von Hippel-Lindau complex including two patients who were operated upon for an associated spinal haemangioblastoma. Of particular interest was a patient who had neurofibromatosis. There was no perioperative deaths. Patients with solid tumours fared badly in the long term compared with those who had a cystic type.

Full text

PDF
165

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Chou S. N., Erickson D. L., Oritiz-Suarez H. J. Surgical treatment of vascular lesions in the brain stem. J Neurosurg. 1975 Jan;42(1):23–31. doi: 10.3171/jns.1975.42.1.0023. [DOI] [PubMed] [Google Scholar]
  2. Gado M., Huete I., Mikhael M. Computerized tomography of infratentorial tumors. Semin Roentgenol. 1977 Apr;12(2):109–120. doi: 10.1016/0037-198x(77)90013-x. [DOI] [PubMed] [Google Scholar]
  3. Jeffreys R. Clinical and surgical aspects of posterior fossa haemangioblastomata. J Neurol Neurosurg Psychiatry. 1975 Feb;38(2):105–111. doi: 10.1136/jnnp.38.2.105. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Jeffreys R. Pathological and haematological aspects of posterior fossa haemangioblastomata. J Neurol Neurosurg Psychiatry. 1975 Feb;38(2):112–119. doi: 10.1136/jnnp.38.2.112. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. KRAYENBUHL H., YASARGIL G. Das Kleinhirnhämangiom. Schweiz Med Wochenschr. 1958 Feb 1;88(5):99–104. [PubMed] [Google Scholar]
  6. Mondkar V. P., McKissock W., Russell R. W. Cerebellar haemangioblastomas. Br J Surg. 1967 Jan;54(1):45–49. doi: 10.1002/bjs.1800540112. [DOI] [PubMed] [Google Scholar]
  7. OLIVECRONA H. The cerebellar angioreticulomas. J Neurosurg. 1952 Jul;9(4):317–330. doi: 10.3171/jns.1952.9.4.0317. [DOI] [PubMed] [Google Scholar]
  8. Obrador S., Blazquez M. G. Benign cystic tumours of the cerebellum. Acta Neurochir (Wien) 1975;32(1-2):55–68. doi: 10.1007/BF01405902. [DOI] [PubMed] [Google Scholar]
  9. Obrador S., Martin-Rodriguez J. G. Biological factors involved in the clinical features and surgical management of cerebellar hemangioblastomas. Surg Neurol. 1977 Feb;7(2):79–85. [PubMed] [Google Scholar]
  10. PERLMUTTER I., HORRAX G., POPPEN J. L. Cystic hemangioblastomas of the cerebellum; end results in 25 verified cases. Surg Gynecol Obstet. 1950 Jul;91(1):89–99. [PubMed] [Google Scholar]
  11. Palmer J. J. Haemangioblastomas. A review of 81 cases. Acta Neurochir (Wien) 1972;27(3):125–148. doi: 10.1007/BF01401877. [DOI] [PubMed] [Google Scholar]
  12. SILVER M. L., HENNIGAR G. Cerebellar hemangioma (hemangioblastoma); a clinicopathological review of 40 cases. J Neurosurg. 1952 Sep;9(5):484–494. doi: 10.3171/jns.1952.9.5.0484. [DOI] [PubMed] [Google Scholar]
  13. STEIN A. A., SCHILP A. O., WHITFIELD R. D. The histogenesis of hemangioblastoma of the brain. A review of twenty-one cases. J Neurosurg. 1960 Jul;17:751–761. doi: 10.3171/jns.1960.17.4.0751. [DOI] [PubMed] [Google Scholar]
  14. Singounas E. G. Haemangioblastomas of the central nervous system. Acta Neurochir (Wien) 1978;44(1-2):107–113. doi: 10.1007/BF01401634. [DOI] [PubMed] [Google Scholar]
  15. WALDMANN T. A., LEVIN E. H., BALDWIN M. The association of polycythemia with a cerebellar hemangioblastoma. The production of an erythropoiesis stimulating factor by the tumor. Am J Med. 1961 Aug;31:318–324. doi: 10.1016/0002-9343(61)90120-6. [DOI] [PubMed] [Google Scholar]

Articles from The Ulster Medical Journal are provided here courtesy of Ulster Medical Society

RESOURCES