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Detection and colocalization of CTCF and Scc3/SA1 in ChIP-Chip experiments. (A) Plot of intensity ratios of individual probes within a region of chromosome 6 and detection of a CTCF-binding site by MeDiCHi (see Methods). (B) Plot of intensity ratios of the Scc3/SA1 ChIP-Chip experiment within the same chromosomal region as in A. (C) Frequency histogram of the distances of Scc3/SA1 peaks (P ≤ 0.01) to all CTCF peaks (P ≤ 0.01) within 2,000 bp.
