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Differences in ductal systems between tadpole and frog. (A) Premetamorphic tadpoles have very few ducts compared with (B) adult pancreas. The complex ductal system arises after metamorphosis. (C) Sections of a 2-month-old pElastase-TRDN-GFP frog showing reduced number of ducts. (D) All types of duct cells in control animals (n = 5 per group) were counted in a unit area from H&E-stained sections of NF54 tadpoles (PreMM), 2 month-old frog (2M), and an adult frog. (Scale bar: 40 μm.)
