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. 1998 Dec 8;95(25):14757–14762. doi: 10.1073/pnas.95.25.14757

Figure 1.

Figure 1

Map of the Chinese hamster ovary DHFR initiation zone. The convergently transcribed DHFR and 2BE2121 genes are shown, as well as the two preferred initiation regions (ori-β and ori-γ) and the matrix attachment region (M) (31). EcoRI and HindIII sites are shown, and the approximate lengths and positions of the probes are indicated below the map (see Materials and Methods for details). The centers of the ori-β and ori-γ regions lie ≈1.2 and 0.25 kb in from the 3′ end of their respective HindIII fragments (23).