Fig. 13.

CBI (mean and individual values) and ocular dominance in normal and monocularly deprived animals after different deprivation protocols. A, Single neuron responses in normal mice are dominated by the contralateral eye (mean CBI = 0.75). After monocular deprivation, CBIs in the visual cortex ipsilateral to the open eye decrease to 0.45 and 0.39 after 20 and 40 d of MD, respectively, indicating dominance of the ipsilateral eye. Late MD, from P40 to 60, is still able to affect the eye dominance of visual cortical neurons. B–E, Percent of cells assigned to each of the seven ocular dominance classes (Hubel and Wiesel, 1962) in normal animals and in animals monocularly deprived from P20 to P40, from P20 to P60, and from P40 to P60, respectively. The number on top of each ocular dominance class indicates the actual number of cells.