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. 2008 Jul 1;99(1):118–125. doi: 10.1038/sj.bjc.6604465

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Copyright © 2008 Cancer Research UK

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MeSC fail to undergo apoptosis after vincristine treatment. (A) Cells treated with 1 nM vincristine for 24 h were double stained with PI and AV and analysed by FACS. An increase in PI⁺/AV⁺ and PI⁻/AV⁺ cells was detected in vincristine-treated SkSC compared to MeSC. (B) The average numbers of early apoptotic AV⁺ cells from two experiments were plotted. ^*Results are statistically significant (P<0.05) by student's t-test.