Table 4. Adolescent hormone levels by birth size among 62 Norwegian girls in the follicular phasea of the menstrual cycle.
|
Geometric meanb (95 % CI)
|
||||
|---|---|---|---|---|
| Variables | No. of girls | Free testosterone index | Androstenedione (nmol l−1) | Estradiol (nmol l−1) |
| Birth length (cm) | ||||
| <49.0 | 26 | 2.16 (1.61–2.90) | 8.0 (7.1–9.1) | 0.08 (0.05–0.12) |
| 49.0–51.0 | 17 | 2.17 (1.50–3.13) | 8.2 (7.1–9.6) | 0.10 (0.06–0.17) |
| ⩾51.0 | 19 | 2.15 (1.53–3.02) | 8.2 (7.1–9.4) | 0.12 (0.07–0.19) |
| Trend testc | eβ=1.00, P=0.98 | eβ=1.01, P=0.81 | eβ=1.24, P=0.17 | |
| Birth weight (g) | ||||
| <3200 | 26 | 2.01 (1.52–2.66) | 7.9 (7.0–8.9) | 0.08 (0.05–0.12) |
| 3200–3700 | 21 | 2.64 (1.93–3.61) | 8.4 (7.4–9.6) | 0.10 (0.06–0.16) |
| ⩾3700 | 15 | 1.83 (1.26–2.67) | 8.3 (7.1–9.7) | 0.13 (0.07–0.21) |
| Trend testc | eβ=0.98, P=0.90 | eβ=1.03, P=0.54 | eβ=1.28, P=0.14 | |
| Ponderal index (g cm−3) | ||||
| <2.63 | 24 | 2.04 (1.53–2.72) | 8.2 (7.2–9.2) | 0.08 (0.05–0.13) |
| 2.63–2.85 | 18 | 2.63 (1.84–3.77) | 7.8 (6.7–9.1) | 0.10 (0.06–0.17) |
| ⩾2.85 | 20 | 1.98 (1.42–2.75) | 8.4 (7.3–9.6) | 0.11 (0.07–0.18) |
| Trend testc | eβ=0.99, P=0.92 | eβ=1.01, P=0.82 | eβ=1.15, P=0.39 | |
| Head circumference (cm) | ||||
| <34.2 | 24 | 2.03 (1.51–2.72) | 7.8 (6.9–8.8) | 0.09 (0.06–0.15) |
| 34.2–35.4 | 23 | 2.34 (1.68–3.24) | 8.1 (7.1–9.2) | 0.09 (0.06–0.15) |
| ⩾35.4 | 14 | 2.12 (1.44–3.12) | 8.8 (7.5–10.3) | 0.10 (0.06–0.17) |
| Trend testc | eβ=1.03, P=0.78 | eβ=1.06, P=0.23 | eβ=1.01, P=0.94 | |
| Skin-fold thickness (mm) | ||||
| <3.8 | 25 | 2.19 (1.64–2.91) | 8.2 (7.2–9.2) | 0.07 (0.05–0.11) |
| 3.8–4.8 | 21 | 1.62 (1.16–2.27) | 7.4 (6.4–8.5) | 0.11 (0.07–0.17) |
| ⩾4.8 | 14 | 2.99 (2.02–4.44) | 9.2 (7.7–10.8) | 0.14 (0.08–0.25) |
| Trend testc | eβ=1.13, P=0.33 | eβ=1.05, P=0.40 | eβ=1.43, P=0.049 | |
CI=confidence interval.
Girls who were measured between day 1 and day 12 of their menstrual cycle and who had LH<10 U l−1, 17-OH-progesterone <10 nmol l−1 and progesterone <5 nmol l−1.
Adjusted for age at puberty, time since menarche, day of menstrual cycle and district.
eβ × 100% equals percent change in hormone levels with increasing birth size category and corresponding P-value.