Table 3. Toxicity during neo-adjuvant chemotherapy and CRT.
|
Neo-adjuvant chemotherapy
|
CRT
|
|||
|---|---|---|---|---|
| Grades 1/2 | Grades 3/4 | Grade 1/2 | Grade 3 | |
| Anaemia (%) | 26 (20) | 0 | 71 (55) | 2 (1.5) |
| Neutropenia (%) | 17 (13) | 7 (5) | 26 (20) | 4 (3) |
| Thrombocytopenia (%) | 1 (0.8) | 1 (0.8) | 5 (4) | 0 |
| Ototoxicity (%) | 1 (0.8) | 0 | 0 | 0 |
| Nausea and Vomiting (%) | 13 (10) | 4 (3) | 15 (11) | 5 (4) |
| Neurotoxicity (%) | 0 | 0 | 1 (0.8) | 0 |
| Cardiac toxicity (%) | 8 (6) | 0 | NA | NA |
| Nephrotoxicity (%) | 5 (4) | 0 | 8 (6) | 1 (0.8) |
| Skin reaction (%) | NA | NA | 103 (77) | 26 (23) |
| Mucositis (%) | 0 | 0 | 51 (40) | 78 (60) |
| Dysphagia (%) | NA | NA | 36 (28) | 85 (72) |
NA=not applicable.