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Effect of curcumin on fed blood glucose levels in obese, diabetic mice. Dietary curcumin significantly lowered random blood glucose levels in both male C57BL/6J DIO (A) and ob/ob (B) mice over the course of a 6-wk period. Blood glucose levels in the ob/ob mice receiving the control diet normalized spontaneously over time due to their propensity to pancreatic islet hyperplasia and hyperinsulinemia (n = 5 per group). *, P < 0.05 by two-tailed t test.
