Figure 8.

Effect of curcumin on adipose expression of cytokine and stress response genes. Dietary curcumin significantly increases expression of adiponectin (Acdc) and decreases F4/80 (Emr1) expression in perigonadal white adipose tissue of male ob/ob mice after 10 wk (A). Curcumin treatment also induced a dramatic effect on ER stress response perigonadal fat gene transcription with significant increases in the expression of Sirt1, HSP70, HSP90, and FOXO1a (B) (n = 5 per group). *, P < 0.05 by two-tailed t test.