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. 2008 Apr 10;149(7):3346–3354. doi: 10.1210/en.2007-0945

Figure 6.

Figure 6

Effect of leptin on whole hypothalamic neuropeptide and Socs-3 mRNA in 24-wk-old CON and DEL littermates. Twenty-four-week-old CON (n = 9) and DEL (n = 9) mice had food removed on d 1. On the same day, mice from each group were injected with 5 mg/kg ip leptin (n = 5/group) or vehicle (n = 4/group) at 1000 and 1600 h. On the following day, the same mice were injected again with leptin (5 mg/kg ip) or vehicle at 0900 h and were killed 1 h later. *, P < 0.05; ***, P < 0.001. Values are means ± sem.