Table 1.
Experimental groups | No. of mice in group | No. of mice with metastases in internal organs | No. of mice with metastases in liver | No. of mice with metastases in spleen | No. of mice with metastases in kidney |
PBS | 9 | 9 | 6 | 7 | 3 |
OncSyn | 7 | 4 | 2 | 2 | 0 |
OncdSyn | 7 | 3 | 1 | 2 | 0 |
Experimental animals were sacrificed on day 42 post-injection of 4T1 cells and the internal organs were removed and examined for metastases formation by gross pathological evaluation as described in Materials and Methods.