Table 1.
Patients' baseline characteristics
| C | D | DN | ||
| Patients | 21 | 27 | 19 | |
| Male/Female | 13/8 | 19/8 | 10/9 | |
| Age (years) | mean (SD) | 56.6 (11.8) | 52.7 (12.7) | 53.7 (10.4) |
| BMI (Kg/m2) | mean (SD) | 25.0 (3.1) | 25.3 (3.4) | 27.0 (4.9) |
| Type 1/Type 2 | - | 8/19 | 9/10 | |
| Diab. Duration (years) | mean (SD) | - | 15.1 (9.3) | 19.4 (9.3) |
| HbA1c (%) ° | mean (SD) | - | 7.5 (1.5) | 7.8 (1.8) |
| VPT toe (Volt) | mean (SD) | 5.3 (2.1) | 14.7 (5.7) | 31.5 (7.6) * |
| NDS | 0 | 3.8 [0–5] | 6.95 [6–8]* | |
| Retinopathy (a/b/p) | - | 24/0/3 | 9/5/5 | |
| Nephropathy (a/m/M) | - | 26/1/0 | 16/2/1 |
C: controls; D: diabetic patients without neuropathy; DN: diabetic patients with neuropathy
SD: standard deviation
* D vs DN; Student's t-test, p < 0.05
a/b/p = absent, background, proliferative;
a/m/M = absent/microalbuminuria/macroalbuminuria
° normal range: 4.3 – 5.9%.