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. 2008 Feb 26;116(7):854–862. doi: 10.1289/ehp.10467

Figure 8.

Figure 8

NAC protection against Cd2+ damage in sections of cochlear explants from rats. (A) Sections of explants from apical, middle, and basal turns of rat cochlea incubated with Cd2+ alone or Cd2+ + NAC and stained with TRITC-conjugated phalloidin. NAC treatment showed a protective effect against the Cd2+ toxic effect. (B) Sections of basal turns of cochlea explants stained with TRITC-conjugated phalloidin (red), DAPI (blue), and TUNEL (green) and examined at a magnification of 100×. In (A) and (B), bar = 50 μm. (C) Percentages of TUNEL-positive cells in different groups of cells.

*p < 0.05 compared with untreated control explants. #p < 0.05 compared with Cd2+ alone.