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. 2008 Mar 24;116(7):930–936. doi: 10.1289/ehp.11068

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LC/MS of brevetoxin–nucleic acid adducts formed by brevetoxin reaction in rat lung after intratracheal exposure. Rel Int, relative intensity. (A–C) Extracted ion current (m/z 860–1,400) from total ion chromatograms, mass spectra, and product ion spectra for (A) brevetoxin–guanosine m/z 1,194, (B) brevetoxin–adenine m/z 1046, and (C) brevetoxin–adenosine m/z 1,178, respectively. The brevetoxin adduct fragment patterns shown in the spectra of (A–C) depict a hypothetical nucleoside linkage to the epoxide to illustrate potential nucleoside or nucleotide fragmentation.