Fig. 2.

Cytotoxic granule release by lymphocytes stimulated using live non-typeable Haemophilus influenzae (NTHi) in control (n = 15) and bronchiectasis (n = 14) subjects. CD107a expression was measured using flow cytometry. (a) Production of CD107 and interferon (IFN)-γ by cytotoxic T cells. Levels of CD107a expression were similar in both groups. Only a small proportion (< 10%) of cytotoxic lymphocyte (CTL) cells stained for both CD107a and IFN-γ. (b) Production of CD107a and IFN-γ by natural killer (NK) cells. Levels of CD107a and CD107a/IFN-γ production were similar in both groups. (c) Shows an example of CD107a production by CTL cells in a control subject in response to stimulation with Staphylococcus enterotoxin-B and to NTHi and NK cell response to NTHi.