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Effect of blockade of major histocompatibility complex (MHC)-I on interferon (IFN)-γ production by cytotoxic T cells; in control subjects (n = 5). (a) MHC-I blockage in controls produced a 70% reduction in expression of IFN-γ by cytotoxic lymphocyte cells that had been stimulated with non-typeable Haemophilus influenzae (NTHi) (*P = 0·033). (b) Cytokine staining for MHC-I block in subject. IL, interleukin; CTL, cytotoxic T lymphocytes.
