Fig. 5.

Response of cytotoxic T cells and natural killer (NK) cells to stimulation with four different isolates of non-typeable Haemophilus influenzae in controls (n = 5). All four different isolates produced measurable interferon (IFN)-γ and CD107a expression, but there were some differences between strains. (a) Cytotoxic lymphocyte (CTL) cell production of IFN-γ with strain 1 (MU/MMC 1) producing higher levels of IFN-γ than strain 4 (*P = 0·021). (b) NK cell production of IFN-γ with strain 1 producing significantly higher levels of IFN-γ than strain 3 (**P = 0·004) and strain 4 (**P = 0·003). (c) CTL production of CD107a. (d) NK cell production of CD107. Differences between different groups were analysed using analysis of variance.