Table I.

Analysis of MLH1 focus frequencies.

Controls	Autosomal MLH1 foci per cell		% cells with an autosomal bivalent containing 0 MLH1	% cells with 0 MLH1 foci in the sex body
	Mean	Range
1	53.2	37–62	5	10.0
2	49.2	32–60	4	9.0
3	49.9	33–61	7	20.0
4	49.9	40–60	6	10.0
5	50.7	38–59	2	15.0
6	51.5	37–63	1	19.0
Mean	50.7	32–63	4.2	13.8
NOA	Autosomal MLH1 foci per cell		% cells with an autosomal bivalent containing 0 MLH1	% cells with 0 MLH1 foci in the sex body
	Mean	Range
7	45.2	20–54	23	14.9
8	48.9	23–61	7	23.0
9	42.7	15–61	16	38.0
10	55.7	44–65	0	3.0
11	45.0	12–57	18	21.0
12	48.4	27–62	18	37.0
13	53.2	25–67	3	18.2
Mean	48.4	12–67	12.4*	22.3

One hundred pachytene stage spermatocytes were analyzed for all control donors and for 5 NOA patients; 87 and 99 pachytene stage spermatocytes were analyzed for NOA patients 7 and 13, respectively.

*P = 0.024 compared with controls.