. Author manuscript; available in PMC: 2009 Sep 1.

Published in final edited form as: Pharmacol Biochem Behav. 2008 Apr 4;90(3):453–462. doi: 10.1016/j.pbb.2008.03.032

Table 3.

ED₅₀ values in mg/kg for cocaine and each RTI compound to substitute for cocaine in the cocaine-discrimination procedure. 95% confidence limits are shown in parentheses.

Drug	ED₅₀ (95% CL)
Cocaine	0.11 (0.065–0.18)
RTI-112	0.018 (0.018–0.018)
RTI-113	0.043 (0.034–0.054)
RTI-150	0.084 (0.065–0.11)
RTI-177	0.59 (0.51–0.68)
RTI-336	2.7 (2.4–3.1)