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Peak responding (percent control) in reinstatement of previously extinguished self-administration behavior.
| RLk | RSo | RVt | Mean ± SEM | |
|---|---|---|---|---|
| saline | 20.4 | 19.0 | 16.2 | 18.5 ± 1.2 |
| cocaine | 73.5 | 114.7 | 57.3 | 81.8 ± 17.1 |
| RTI-112 | 43.1 | 68.1 | 93.7 | 68.3 ± 14.6 |
| RTI-113 | 45.7 | 122.3 | 105.5 | 91.2 ± 23.3 |
| RTI-150 | 116.9 | 42.8 | 23.0 | 60.9 ± 28.6 |
| RTI-177 | 94.0 | 73.0 | 142.7 | 103.2 ± 20.7 |
| RTI-336 | 45.1 | 116.3 | 50.8 | 70.7 ± 22.9 |
