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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: Pharmacol Ther. 2008 Feb 9;118(1):1–17. doi: 10.1016/j.pharmthera.2007.12.004

Figure 3.

Figure 3

Scatchard analysis of [3H]-R-PK11195 binding to TSPO in the cerebral cortex of animals exposed to cuprizone for 4 weeks. The data clearly show that the effect of cuprizone treatment on [3H]-R-PK11195 specific binding is in the maximal number of binding sies (Bmax) and not in the affinity (Kd). Published with permission from Oxford University Press. Taken from Chen et al., Brain 127: 1379–1392, 2004.