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. 2008 Jul;57(7):1824–1833. doi: 10.2337/db07-0435

FIG. 5.

FIG. 5.

Elevated plasma adiponectin has no effect on hepatic VLDL-TG secretion and lipoprotein particle size. A and B: Hepatic VLDL-TG secretion rates were studied by measuring serum TG accumulation using Poloxamer-407 to inhibit endogenous LPL. The mice were fasted for 4 h, 3 days after viral vector injection. Blood samples were collected at indicated time points, and TG was measured. C and D: Four-hour fasting blood samples were collected 3 days after virus injection. Mean lipoprotein particle size and subclass profile were measured using a proton NMR analyzer, n = 6. Diameter range for VLDL subclass: large, >60 nm; medium, 35–60 nm; small, 27–35 nm. *P < 0.05 vs. Ad-GFP vector–treated control mice.