TABLE 1.

Transgenic PD-L1 moderately prolongs the survival period of grafts in isogenic islet transplantation

Donor islets	Graft survival of each recipient (days)	Mean survival period (days)
NOD	5, 5, 5, 6, 6, 6, 7, 9	6.1
L1C	5, 6, 7, 7, 7, 9, 9, 13	7.9

Pancreatic islets isolated from 6- to 8-week-old mice were transplanted into recipients that were newly diagnosed with diabetes. Blood glucose concentration of recipients was monitored every day. The recurrence of diabetes among the recipients was defined as a recipient blood glucose concentration >16.7 mmol/l in two consecutive evaluations. The day of diabetic recurrence was considered as the end of islet survival.