TABLE 2.

Circulating arterialized metabolite concentrations during baseline and isoprenaline infusion in lean and obese subjects

	Lean			Obese
	Baseline	ISO	Δ	Baseline	ISO	Δ
n	13	10	10	10	7	7
TAG (μmol/l)	701 ± 66	648 ± 64*	−46 ± 23	1,464 ± 190†	1,667 ± 217*†	112 ± 44‡
FFA (μmol/l)	661 ± 41	942 ± 53*	271 ± 46	638 ± 42	1,124 ± 82*	469 ± 82‡
Glycerol (μmol/l)	102 ± 5	118 ± 7*	15 ± 5	106 ± 4	147 ± 10*†	44 ± 9‡
Glycerol Ra (μmol/min)	199 ± 12	311 ± 28*	109 ± 13	220 ± 15	391 ± 30*	172 ± 19
Glycerol Ra/FFM (μmol · kg−1 FFM · min−1)	3.4 ± 0.2	5.5 ± 0.5*	2.0 ± 0.5	3.3 ± 0.3	5.8 ± 0.6*	2.5 ± 0.5
Glucose (mmol/l)	5.3 ± 0.1	5.4 ± 0.1	0.14 ± 0.06	5.5 ± 0.2	5.4 ± 0.1	−0.12 ± 0.10
Insulin (mU/l)	7.2 ± 0.6	10.7 ± 0.9*	3.4 ± 0.6	13.6 ± 1.0†	24.0 ± 2.3*†	10.6 ± 1.5‡
Lactate (mmol/l)	0.61 ± 0.04	0.72 ± 0.03	0.09 ± 0.04	0.98 ± 0.11†	0.99 ± 0.06†	0.05 ± 0.07

Data are means ± SE.

^*P < 0.05 ISO vs. baseline.

^†P < 0.05 obese vs. lean.

^‡P < 0.05 change (Δ) from baseline obese vs. lean.