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. 2008 Apr 16;10(2):R43. doi: 10.1186/ar2401

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Copyright © 2008 Richardson et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Levels of the endocannabinoids anandamide (AEA), 2-arachidonyl glycerol (2-AG), palmitoyl ethanolamide (PEA), and oleoyl ethanolamide (OEA) in synovial fluid of non-inflamed normal volunteers (control) (n = 6) and of patients with osteoarthritis (OA) (n = 14) and rheumatoid arthritis (RA) (n = 5). Data were analysed using the non-parametric Mann-Whitney test and are expressed as picomoles per millilitre. **P < 0.01, ***P < 0.005 compared with control values. ^▽P < 0.05 compared with OA values. ND, not detected below a limit of detection of 0.3 pmol/mL.