Table 3.
Univariate analyses for cardiovascular morbidity in patients with rheumatoid arthritis in the QUEST-RA study
| Cardiovascular morbidity (percentage of patients) | |||||
| No | Yes | Hazard ratio | 95% CI | P value | |
| Rheumatoid variables | |||||
| Rheumatoid factor | 71.7 | 77.0 | 1.02 | 0.76–1.37 | 0.881 |
| Extra-articular diseasea | 23.0 | 43.3 | 1.52 | 1.19–1.95 | 0.001 |
| Traditional risk factors | |||||
| Age in years (mean) | 55.8 | 66.4 | 1.05 | 1.04–1.06 | 0.000 |
| Gender (female) | 79.4 | 64.0 | 0.42 | 0.33–0.54 | 0.000 |
| Hypertension | 28.7 | 62.9 | 2.97 | 2.31–3.83 | 0.000 |
| Hyperlipidemia | 11.3 | 34.0 | 3.19 | 2.47–4.13 | 0.000 |
| Diabetes | 6.9 | 15.8 | 2.09 | 1.50–2.92 | 0.000 |
| Smoking ever | 42.6 | 51.2 | 1.60 | 1.25–2.04 | 0.000 |
| Smoking now | 18.3 | 11.8 | 0.80 | 0.55–1.18 | 0.260 |
| Obesity | 17.5 | 18.3 | 1.34 | 0.96–1.86 | 0.082 |
| Physical inactivity | 71.9 | 73.5 | 1.00 | 0.75–1.33 | 0.993 |
aIncludes nodules, pulmonal fibrosis, pericarditis, vasculitis, Felty syndrome, and scleritis. CI, confidence interval; QUEST-RA, Questionnaires in Standard Monitoring of Patients with Rheumatoid Arthritis.