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Chloroquine selectively kills dendritic cells exposed to IL-6. Equal numbers of dendritic cells derived from day-6 bone marrow cultures were incubated overnight with GM-CSF or GM-CSF plus IL-6 with or without 20 μM chloroquine. The next day nonadherent dendritic cells were counted, and the ratios of the number of cells from cultures treated or untreated with chloroquine (CQ) from four experiments were calculated and plotted as shown.
