Table 3.

Ornithine decarboxylase activity and ear swelling in TPA-treated C3H mice

Hours after treatment	ODC activity		Ear swelling
	C3H/HeN	C3H.SW	C3H/HeN	C3H.SW
0	78  ± 9	72  ± 4
6	1824  ± 174	1732  ± 139	33.8  ± 3.3	37.8  ± 3.0
24	82  ± 12	79  ± 11	35.9  ± 3.8	40.6  ± 3.5

Four animals in each group were treated topically with TPA (40 nmol) and ODC activity was determined in epidermal cytosol as described in Materials and Methods. Data represent four independent values from each assay, conducted in triplicate. Four animals in each group were treated topically with TPA (32.4 nmol) and ear swelling was determined by measuring ear swelling in triplicate as described in Materials and Methods. The data are one of two representative experiments. Values given are mean ± SEM. None of the values in this table is statistically significant.