Table 2.

Comparison of the immunoenhanced Pap test with the conventional pathological diagnosis

Classification by Anti-Mcm5 test	Classification by conventional criteria
	Normal	LSIL	HSIL	Adeno-Carc.
Negative	26	0	0	0
Positive	4*,†	9	16‡	3
Total	30	9	16	3

^*Two smears that were reported normal by the conventional Pap test stained positively by anti-Mcm5 antibody. On this basis the patients were recalled and were shown histologically (approximately 6 months after the original smear) to have HSIL. 

^†Two antibody-positive smears were found to contain just immature metaplastic squamous cells, which were recognized by conventional criteria using the underlying Pap stain on the same slide. 

^‡Of these 16 cases, 12 were confirmed by both Pap smear and histology.