Table 1.

Behavioral parameters of 2 month old female and male PCAF KO and WT mice in the open-field test

Parameter	Female		Male
	WT	PCAF KO	WT	PCAF KO
Weight (g)	22.7 ± 0.9	22.0 ± 0.6	29.1 ± 0.9	27.9 ± 1.1
Latency to start (s)	5 ± 2	10 ± 3	15 ± 5	16 ± 4
Locomotion (m)	17.2 ± 1.6	13.8 ± 2.1	19.6 ± 2.9	18.3 ± 3.2
Loc. in center (%)	15.5 ± 3.9	9.1 ± 2.6	15.3 ± 2.7	18.0 ± 4.8
Speed (m/min)	2.56 ± 0.13	2.10 ± 0.17	2. 66 ± 0.31	2.54 ± 0.25
Immobility (s)	196 ± 20	210 ± 34	139 ± 25	146 ± 38
Rearing	10 ± 3	8 ± 3	15 ± 6	15 ± 5
Grooming	6 ± 1	5 ± 1	6 ± 1	5 ± 1
Defecations	4 ± 1	5 ± 1	5 ± 1	5 ± 1
n	7	8	9	8

Results were analyzed using a two-way ANOVA, with substrain and gender as independent factors and no behavioral parameters showed significant variations.