Skip to main content
. Author manuscript; available in PMC: 2009 May 7.
Published in final edited form as: J Theor Biol. 2008 Jan 20;252(1):24–38. doi: 10.1016/j.jtbi.2008.01.010

Table 2.

Sensitivity of M. tuberculosis numbers (100 hours post-infection) to quantitative variations in regulatory interactions

Partial Rank Correlations with Mtb # NO regulation of:1
NF-κB Stat1 IRP2
Control graphic file with name nihms49484t1.jpg graphic file with name nihms49484t2.jpg graphic file with name nihms49484t3.jpg
Scenario 1
Scenario 2
Scenario 3
*

p<0.01. The far right bracket for each parameter denotes significant differences between Control and each numbered scenario. The remaining two brackets denote significant changes between the three numbered scenarios. NS: not significantly different from zero (p > 0.01).

1

Due to negative regulation by these interactions, correlations with negative signs are interpreted to mean that stronger negative regulation reduces the effectiveness of M. tuberculosis killing.

2

IRP: Iron response protein. See Figure 2.