Table 1.
Baseline demographic, clinical and MRI characteristics of the patients, grouped by absence or presence of CMR late gadolinium enhancement (LGE).
| Variable | LGE ABSENT BY CMR (N=38) | LGE PRESENT BY CMR (N=27) | p-value |
|---|---|---|---|
| Age - yrs | 55±12 | 56±9 | P=0.99 |
| Male gender – no. (%) | 19 (50) | 23 (85) | P=0.003 |
| Caucasian – no. (%) | 19 (50) | 15 (58) | P=0.14 |
| Duration of cardiomyopathy diagnosis (years) | 4.0±4.1 | 4.1±4.4 | P=0.74 |
| Entry EF (non-MRI method) (%) | 21±9 | 19±6 | P=0.47 |
| Single vessel CAD >50% (non-left main or proximal LAD vessels) | 2 (5) | 3 (11) | P=0.38 |
| NYHA functional class | P=0.52 | ||
| Class I | 7 (18) | 3 (11) | |
| Class II | 16 (42) | 15 (56) | |
| Class III | 15 (39) | 9 (33) | |
| Medication use – no.(%) | |||
| ACEI or ARB | 33 (87) | 25 (92) | P=0.46 |
| Beta-blocker | 36 (95) | 24 (89) | P=0.64 |
| Diuretic | 22 (65) | 19 (73) | P=0.38 |
| Spironolactone | 11 (29) | 8 (30) | P=0.95 |
| Digoxin | 15 (39) | 5 (19) | P=0.07 |
| Antiarrhythmics (amiodarone) | 2 (5) | 4 (15) | P=0.19 |
| Lipid-lowering | 16 (42) | 16 (59) | P=0.17 |
| Received biventricular ICD (%) | 15 (41) | 8 (30) | P=0.37 |
| CMR measurements | |||
| LVEF (%) | 26±9 | 22±10 | P=0.20 |
| LVEDV index (ml/m2) (all patients) | 126±43 | 149±64 | P=0.10 |
| Female | 120±37 | 137±96 | |
| Male | 132±49 | 151±67 | |
| LVESV index (ml/m2) (all patients) | 96±41 | 120±66 | P=0.08 |
| Female | 89±36 | 109±44 | |
| Male | 104±50 | 122±69 | |
| LV mass (grams/m2) (all patients) | 78±24 | 90±43 | P=0.16 |
| Female | 73±17 | 71±21 | |
| Male | 83±29 | 93±45 | |
| Extent of LGE (mean±SD) | -- | 10±13% of LV mass | -- |
| Median extent | 5% | ||
| Interquartile range | 3–16% | ||
| Total volume (ml) | 17±21 ml |