Plasma total cholesterol levels were significantly increased in all ApoEKO mice compared to B6 control. *, p<0.05, comparing lupus-prone-ApoEKO and corresponding controls. #, p<0.05, comparing MRL/lpr and B6 control. +, p<0.05, comparing B6/lpr.ApoE-/- and B6.ApoE-/-; and comparing MRL/lpr.ApoE-/- and B6.ApoE-/-, respectively. For each strain, data are pooled from 5 females and 4 males.