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. Author manuscript; available in PMC: 2009 May 1.
Published in final edited form as: J Oral Maxillofac Surg. 2008 May;66(5):987–994. doi: 10.1016/j.joms.2008.01.038

Figure 3.

Figure 3

Bisphosphonates significantly reduce intracortical bone formation rate in the mandible. There was a significant reduction in the overall bone formation rate of the mandible with both doses of alendronate (ALN) or when the two doses of ALN were pooled. There was no significant difference between the two doses of ALN. The greatest suppression of turnover was noted in the alveolar portion of the mandible with no significant effect of ALN treatment on turnover suppression in the non-alveolar portion. Across all groups turnover was 84% lower in the non-alveolar region compared to the alveolar region. * p < 0.05 versus VEH.