Figure 6.
Immunoglobulin isotypes profiles, IgG1 and IgG2a, of anti-MSP1-19 antibodies from IL-4 KO, STAT6 KO and WT mice immunized with P30P2MSP1-19 in different adjuvant formulations. Panel A, ISA720; Panel B, ISA720/QS21 Panel C: ISA720/MPL; Panel D, ISA720/QS21/MPL. Symbols: black bars, IgG1; light grey bars, IgG2a. Significant differences in the Ig isotype responses (Student t test) between the WT and KO mice of an adjuvant group are indicated by asterisks above the corresponding Ig isotype.