Table 1 Percentage changes in blood clotting in normal volunteers infused with 1000 ml of 0.9% saline or Gelofusine.
| Percentage change from control | ||
|---|---|---|
| Saline | Gelofusine | |
| Sonoclot time to peak | −3% (−40% to +34%) | +96% (+42% to +151%) |
| Sonoclot clot rate | 6% (−9% to 21%) | −12% (−19% to –4%) |
| Sonoclot ACT | −15% (−6% to −25%) | −6% (−14% to 2%) |
| INR | +1% (−1% to +4%) | +4% (−1% to +9%) |
| APTT | −2% (−6% to +3%) | +1% (−5% to +6%) |
| TT | 0% (−5% to +5%) | +3% (−2% to +8%) |
| D‐dimer (ng/ml) | +51% (−48% to +150%) | +41% (−28% to +111%) |
| Tissue factor ag (pg/ml) | −1% (−7% to +5%) | +11% (−10% to +32%) |
| Antithrombin III (IU/ml) | 0% (−7% to +6%) | +1% (−11% to +13%) |
| vWF ag (%) | −1% (−3% to +1%) | +4% (−6% to +13%) |
| Fibrinogen (mg/dl) | −4% (−12% to +4%) | −1% (−20% to +18%) |
ACT, activated clotting time; ag, antigen; APTT, activated partial thromboplastin time; INR, international normalised ratio; TT, thromboplastin time; vWF ag; von‐Willebrand factor antigen.