Table 2 Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy (%, with 95% confidence intervals) of the anion gap for predicting the presence of lactic acidosis at different anion gap thresholds.

Threshold	Sensitivity	Specificity	PPV	NPV	Accuracy
AG >6	93.2 (86.8–99.6)	17.3 (12.6–22.1)	20.5 (15.6–25.5)	91.8 (84.2–99.5)	31.7 (26.4–36.9)
AG >12	58.2 (45.1–71.2)	81.0 (76.2–85.9)	40.5 (29.7–51.3)	89.7 (85.8–93.7)	76.9 (72.2–81.6)