Table 1.
Microarray Platform | Pc < 0.001# | Pc < 0.05 & FC > 2 ## | Best 3800 probes### |
Affymetrix |
1877 genes (1908 probe sets) |
1914 genes (1945 probe sets) |
3738 genes 0.05 < Pc < 10-11 0.48 < |log 2 FC| < 10.38 |
Illumina |
1993 genes (2010 probes) |
845 genes (854 probes) |
3761 genes 0.05 < Pc < 10-11 0.26 < |log 2 FC| < 6.92 |
Reference list (RNG-86) |
5204 genes (5677 probes) |
894 genes (933 probes) |
3552 gene 0.05 < Pc < 10-79 0.34 < |log 2 FC| < 6.91 |
Number of differentially expressed genes between macrophage and monocyte samples using different criteria for selecting lists. The analysis was performed on the subset of well-matched transcripts common to the three platforms [see Additional file 5] for the number of probes included in this analysis for each platform).
# adjusted P-value (Pc) of the moderated t test.
## adjusted P-value of the moderated t test combined to fold change (FC).
### best overlapping lists of genes among platforms (see results section for details).