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. 2008 Jul 30;3(7):e2788. doi: 10.1371/journal.pone.0002788

Table 2. Validity of ADA as a diagnostic test.

Cases Sensitivity % (CI) Specificity % (CI) PPV % (CI) NPV (%) (CI) LR+ (CI) LR− (CI)
Confirmed TB pleuritis (n = 72) 94 (86–98) 95 (82–99) 97 (89–99) 90 (76–97) 18.9 (4.9–73 0.06 (0.02–0.15)
Clinical TB (n = 125) 94 (88–97) 95 (82–99) 98 (93–100) 84 (70–93) 18.9 (4.9–73.0) 0.06 (0.03–0.12)
Total TB Pleuritis (n = 197) 94 (90–97) 95 (82–99) 99 (96–100 77.5 (63–88) 18.9 (4.9–72.9) 0.06 (0.03–0.10)

PPV = positive predictive value; NPV = negative predictive value; CI = 95% confidence interval; LR+ = positive likelihood ratio; LR− = negative likelihood ratio.