Table 4.
Number of cardiovascular procedures in CHARM
| Procedure | CHARM-Alternative | CHARM-Added | CHARM-Preserved | CHARM-Overall | ||||
|---|---|---|---|---|---|---|---|---|
| Placebo (n = 1015) |
Candesartan (n = 1013) |
Placebo (n = 1272) |
Candesartan (n = 1276) |
Placebo (n = 1509) |
Candesartan (n = 1514) |
Placebo (n = 3796) |
Candesartan (n = 3803) |
|
| Cardiac catheterization incl. angiography | 160 | 139 | 228 | 172 | 261 | 262 | 649 | 573 |
| CABG | 26 | 21 | 22 | 39 | 42 | 46 | 90 | 106 |
| PTCA with stent | 31 | 30 | 55 | 36 | 73 | 78 | 159 | 144 |
| PTCA without stent | 11 | 10 | 19 | 10 | 23 | 15 | 53 | 35 |
| Implantation of cardioverter defibrillator | 31 | 30 | 60 | 51 | 9 | 9 | 100 | 90 |
| Implantation of pacemaker | 50 | 49 | 75 | 80 | 54 | 67 | 179 | 196 |
| Heart transplantation | 8 | 7 | 15 | 17 | 0 | 0 | 23 | 24 |
| Ventricular assist device | 6 | 6 | 3 | 1 | 0 | 1 | 9 | 8 |
| Other cardiac surgery for heart failure | 3 | 2 | 6 | 9 | 10 | 11 | 19 | 22 |
| Other cardiovascular procedure/operation | 112 | 112 | 213 | 188 | 196 | 192 | 521 | 492 |
| Total no. CV procedures | 438 | 406 | 696 | 603 | 668 | 681 | 1802 | 1690 |
| Total no. patients with CV procedure (% of patients) | 239 (23.6) | 218 (21.5) (p = 0.27) | 349 (27.4) | 320 (25.1) (p = 0.18) | 350 (23.2) | 342 (22.6) (p = 0.69) | 938 (24.7) | 880 (23.1) (p = ??) |
Abbreviations: CABG, coronary artery bypass grafting; CV, cardiovascular; PTCA, percutaneous transluminal coronary intervention.