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. 2006 Apr;15(2):122–126. doi: 10.1136/qshc.2005.015347

Table 2 Summary of main findings for unintended variances.

Overall (N = 60) Admission (N = 60) Discharge (N = 56)
No of patients with at least one unintended variance (%, 95% CI) 36 (60%, 48 to 72) 23 (38%, 26 to 51) 23 (41%, 28 to 54)
Mean number of unintended variances per patient (95% CI) 2.3 (1.5 to 3) 1.2 (0.7 to 1.6) 1.2 (0.7 to 1.7)
Types of unintended variances (% of variances)
 Total number of unintended variances 136 (100%) 69 (100%) 67 (100%)
 Omitted medication/prescription 80 (59%) 50 (72%) 30 (45%)
 Incorrect/omitted details (dose, route, frequency) 18 (13%) 15 (22%) 3 (4%)
 Additional medication unintentionally ordered 4 (3%) 4 (6%) 0
 Lack of discharge instruction regarding medication changed in hospital 34 (25%) NA 34 (51%)
No of patients with at least one clinically important unintended variance (%, 95% CI) 11 (18%, 9 to 28) 9 (15%, 6 to 24) 5 (9%, 2 to 16)
Clinically important unintended variances 20 10 10
 Intercepted 15 8 7
 Not intercepted 5 2 3
Variances leading to harm 4 2 2
Physician response to unintended variance
 Order new medication/prescription 21 (15%) 2 (3%) 19 (28%)
 Discontinue or hold medication 3 (2%) 1 (1%) 2 (3%)
 Change details (e.g. dose, route, frequency) 11 (8%) 7 (10%) 4 (6%)
 Restart medication 31 (23%) 22 (32%) 9 (13%)
 No changes made 70 (51%) 37 (54%) 33 (49%)
 Total 136 69 67