No of patients with at least one unintended variance (%, 95% CI) |
36 (60%, 48 to 72) |
23 (38%, 26 to 51) |
23 (41%, 28 to 54) |
Mean number of unintended variances per patient (95% CI) |
2.3 (1.5 to 3) |
1.2 (0.7 to 1.6) |
1.2 (0.7 to 1.7) |
Types of unintended variances (% of variances) |
|
|
|
Total number of unintended variances |
136 (100%) |
69 (100%) |
67 (100%) |
Omitted medication/prescription |
80 (59%) |
50 (72%) |
30 (45%) |
Incorrect/omitted details (dose, route, frequency) |
18 (13%) |
15 (22%) |
3 (4%) |
Additional medication unintentionally ordered |
4 (3%) |
4 (6%) |
0 |
Lack of discharge instruction regarding medication changed in hospital |
34 (25%) |
NA |
34 (51%) |
No of patients with at least one clinically important unintended variance (%, 95% CI) |
11 (18%, 9 to 28) |
9 (15%, 6 to 24) |
5 (9%, 2 to 16) |
Clinically important unintended variances |
20 |
10 |
10 |
Intercepted |
15 |
8 |
7 |
Not intercepted |
5 |
2 |
3 |
Variances leading to harm |
4 |
2 |
2 |
Physician response to unintended variance |
|
|
|
Order new medication/prescription |
21 (15%) |
2 (3%) |
19 (28%) |
Discontinue or hold medication |
3 (2%) |
1 (1%) |
2 (3%) |
Change details (e.g. dose, route, frequency) |
11 (8%) |
7 (10%) |
4 (6%) |
Restart medication |
31 (23%) |
22 (32%) |
9 (13%) |
No changes made |
70 (51%) |
37 (54%) |
33 (49%) |
Total |
136 |
69 |
67 |